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emollient, 30, 44                             lipophilic, 27, 35

               epidermis, 3, 4, 5, 6, 7, 97                  liquid paraffin, 22, 38, 58, 76

               eumelanin, 5                                  log P, 11, 13, 14, 16, 33, 161, 163

                                  F                          lumping, 90

               flocculating agent, 51                                           M

               flocculation, 44                              matrix, 99, 101, 107, 109, 111

               fusion, 72, 80, 182                           melanin, 5

                                  G                          melanocytes, 5

               gelation, 83                                  metabolism, 2, 104, 107, 114

               geometric dilution, 44, 69, 71, 78, 94        micrometer, 145

                                  H                          microneedle, 16

               half-life, 99                                 microreservoir, 103

               homogenizer, 42, 51, 90                       microscope, 142, 145, 146

               hydrolysis, 25, 169                           mineral oil, 22, 38, 53, 58, 59, 62, 75

               hydrophilic, 11, 27, 35, 61, 63               moisturizer, 50

               hydrophobic, 1, 11                                               N

                                   I                         newtonian, 19, 49, 120

               incompatibility, 23, 118                      nonionic, 27, 88

               incorporation, 43, 68, 78                     non-newtonian, 19, 49

               infrared, 142                                                    O

               inorganic, 82                                 occlusive effect, 13, 20, 21, 58

               intercellular, 13                             ophthalmic, 137, 185

               intercellular route, 11                       organic, 82

               iontophoresis, 15                             oswald ripening, 45

               irritation, 133, 136, 189                     oxidation, 169

               isopropyl myristate, 30, 48                                      P

                                  L                          paraben, 25, 29, 34, 49, 50, 63, 64, 68,

               lanolin, 21, 30, 31, 38, 61, 62, 76, 77, 78       84, 89

               levigate, 44                                  partition coefficient, 11, 161, 162



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